Reference:“The use of alpha-lipoic acid (ALA), gamma linolenic acid (GLA) and rehabilitation in the treatment of back pain: effect on health-related quality of life,” Ranieri M, Sciuscio M, et al, Int J Immunopathol Pharmacol, 2009; 22(3 Suppl): 45-50. (Address: Physical Medicine and Rehabilitation Unit, Neurological and Psychiatric Sciences Department, Aldo Moro University, Bari 70124, Italy. E-mail: ranieri@neurol.uniba.it ).
Summary:In a study involving 203 patients with back pain including compressive radiculopathy syndrome from disc-nerve root conflict, supplementation with alpha-lipoic acid (600 mg/d) and gamma-linolenic acid (360 mg), along with participating in a physical rehabilitation program for a period of 6 weeks was found to be more effective than patients who were treated with the physical rehabilitation program alone. Specifically, those who received the ALA + GLA were found to have significantly greater improvements in paresthesias, stabbing and burning pain, Oswestry Low Back Pain Disability Questionnaire, Aberdeen Low Back Pain Scale, and improvements in quality of life, assessed via the SF-36, Revised Leeds Disability Questionnaire, and the Roland and Morris disability questionnaire. The authors conclude, “Oral treatment with alpha-lipoic acid (ALA) and gamma-linolenic acid (GLA) for six weeks in synergy with rehabilitation therapy improved neuropathic symptoms and deficits in pa tients with radicular neuropathy.”
No comments:
Post a Comment